Severe gynaecomastia associated with spironolactone treatment in a patient with decompensated alcoholic liver cirrhosis – Case report
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2015, Vol 9, Issue 1
Abstract
Gynaecomastia is uni- or bilateral breast enlargement in males associated with benign hyperplasia of the glandular, fibrous and adipose tissue resulting from oestrogen-androgen imbalance. Asymptomatic gynaecomastia is a common finding in healthy male adults and does not have to be treated, while symptomatic gynaecomastia might be the symptoma of many pathological conditions and requires meticulous diagnosis and therapeutic management. The commonest causes of gynaecomastia in the Polish population include liver cirrhosis and drugs used to treat its complications. The current study presents the case of severe painless gynaecomastia in a patient with decompensated alcoholic liver cirrhosis, treated with spironolactone because of ascites. Breast enlargement assessed a IIb according to the Simon’s Scale or III according to the Cordova-Moschella classification, developed slowly over the two-year period of low-dose spironolactone therapy The course and dynamics of disease are described and the main mechanisms leading to its development discussed. The importance of effective treatment of patients with severe gynecomastia is emphasized as the disease may result in significant psychosocial problems.
Authors and Affiliations
Katarzyna Schab, Andrzej Prystupa, Dominika Mulawka, Paulina Mulawka
Keywords
Related Articles
- EP ID EP58848
- DOI -
- Views 156
- Downloads 0
The occurrence of Toxoplasma gondii infection in people and animals from rural environment of Lublin region - estimate of potential role of water as a source of infection.
A total of 254 humans and 489 domestic animals living on farms in the Lublin province (eastern Poland) were examined for the presence of antibodies against Toxoplasma gondii using, respectively, the ELFA and direct agglu...
The influence of rural environment on body posture
Looking for reasons for the diversification between the populations of rural and urban children has become very popular in Polish literature. The aim of the presented study is to compare body posture and, at the same tim...
Organic dust induced pulmonary disease - the role of mould derived beta-glucan.
The objective of the study was to evaluate the role of the mould cell wall agent beta-glucan in environmentally related pulmonary disease. All published articles where beta-glucan was administered by the airways, either...
Change in airway inflammatory markers in Danish energy plant workers during a working week
[b]Introduction.[/b] It is well known that exposure to organic dust can cause adverse respiratory effect. The pathogen-associated molecular patterns (PAMPS) in the organic dust, such as endotoxin from Gram-negative bacte...
Impact of beliefs about pain control on perceptions of illness in surgical patients
[b][/b][b]Objectives.[/b] Adequacy of pain management in surgical patients is a major contributor to overall treatment outcomes and positive illness perceptions. However, it may be subjectively predetermined by a patient...