Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease): A Case Report with Review of Literature
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 3
Abstract
Sinus Histiocytosis with Massive lymphadenopathy, also commonly known as Rosai-Dorfman Disease is a rare non neoplastic histiocytic disorder first described by Rosai and Dorfman, seen predominantly in childhood and young adults. It is characterized by fever, painless massive cervical lymphadenopathy and elevated ESR levels. RDD is often misdiagnosed as lymphoma, tuberculosis or metastatic malignancy, so it is important to distinguish it from these conditions as the modes of treatment are different. Here we report a case of 18 years old male presenting with massive lymphadenopathy. Morphological findings demonstrated Emperipolesis consistent with a diagnosis of Rosai-Dorfman disease. Clinical and cytological aspects of the disease are discussed as a rare cause of lymphadenopathy.
Authors and Affiliations
Dr Rajat Gupta
Keywords
Related Articles
- EP ID EP213427
- DOI -
- Views 120
- Downloads 0
Malocclusion of Permanent Teeth in Primary School Children (6-12 Yrs) is A Risk Factor for Caries Teeth
Dental health is a part of school health services. Dental caries and peridontal disease are the two common dental diseases in India. Prophylactic cleansing is of great value in preventing gum diseases and in improving pe...
Growth and Neurodevelopmental Outcome of Very Low Birth Weight Babies at 1 Year of Age
Background: Advances in perinatal care and improved neonatal services have improved the survival rates of very low birth weight (VLBW) babies. The risk of neurodevelopmental deficit increases as gestational age decreases...
Clinical Study of Coma in Children
Background: Coma is a state of unarousable psychogenic unresponsiveness, in which the subjects lie with eyes closed. It has been an enigma for clinicians for many years and searching for the cause and prognosis is always...
A Correlative Study of Biochemical, Virological & Histological Parameters of HBV Infection in HIV/HBV Co-Infection
Introduction: In the setting of HBV-HIV coinfections, serial monitoring of ALT alone may not predict the severity of HBV disease. This study aims at studying the correlation between ALT, Viral load and the histological p...
Echocardiographical Evaluation And Cardiovascular Changes In Chronic Obstructive Pulmonary Disease Patients In Tertiary Care Hospital
INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is a disease characterized by progressive poorly reversible airway destruction. Cardiovascular disease accounts for significant morbidity and mortality in chroni...