SiRNA- Silencing the Culprits
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Plants as well as animals contain hundreds of small RNAs with distinct genes responsible for their regulation. Any changes in this has corresponding effects on the development and growth of organisms. These small RNAs include microRNA, Piwi-interacting RNA, and short interfering RNA. In case of plants there is complete complimentarity between the microRNA and mRNA, while in animals only partial complimentarity exists. These small RNAs have been used in therapeutics as well as in studying the development process.
Authors and Affiliations
Dr. Neetu Sinha, Dr. Priya Sahni, Dr. Jayadeva HM, Dr. Shylaja MD, Dr. Pawan Gujjar, Dr. Achala Shenoy
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