Sleep quality and mental stress influence salivary melatonin concentrations
Journal Title: Journal of Analytical Bio-Science - Year 2012, Vol 35, Issue 3
Abstract
We compared different factors to explore an association between melatonin and sleep quality. In 26 healthy young women, we measured the salivary melatonin concentration, and used the Pittsburgh sleep quality index (PSQI), State-Trait Anxiety Inventory (STAI), Self-Rating Depression Scale (SDS), and NEO Five-Factor Inventory (NEO-FFI). We obtained additional findings: 1) subjects with a poor sleep quality had a higher nocturnal concentration of salivary melatonin associated with more intensive recent mental stress (as demonstrated by the STAI and SDS scores), and 2) the nocturnal melatonin concentration is recommended 100 pg/mL or below for studying sleep quality using salivary melatonin concentrations as a measure in healthy young women. The results from the present study suggested that nocturnal melatonin was associated with stress scores in the subjects with a poor sleep quality and that most recent mental stress, such as depression and anxiety, may have an impact on the nocturnal melatonin level. Moreover, the nocturnal melatonin concentration should be desirably 100 pg/mL or below, which is considered to be a daily level, for studying sleep quality using a salivary melatonin concentration as a measure in healthy young women.
Authors and Affiliations
Yasumi Taki
Keywords
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