Staphylococcus aureus: Nasal-carriage in Health Care Workers and In-patients with Special Reference to MRSA
Journal Title: Microbiology Research Journal International - Year 2016, Vol 13, Issue 4
Abstract
Aims: To find out the nasal carriage of Staphylococcus aureus in health care workers and in-patients in a tertiary care center. Study Design: Cross sectional study. Place and Duration of Study: Department of Microbiology, Government Medical College and Hospital, Srinagar Kashmir. One year study (July 2013 to June 2014). Methodology: Nasal swabs were taken from health care workers (HCWs) and in-patients and these were processed for the recovery of Staphylococcus aureus (S. aureus) and methicillin resistant Staphylococcus aureus (MRSA). Antimicrobial susceptibility of the isolates to various antibiotics was performed as per Clinical Laboratory Standards Institute (CLSI), guidelines and D-test done to ascertain constitutive macrolide-lincosamide-streptogramin B (cMLSB) and inducible macrolide-lincosamide-streptogramin B (iMLSB) phenotype. Risk factors for their carriage were also analyzed. Statistical analysis was done using SPSS software version 16 and a P value of < 0.05 was taken as significant. Results: Higher rate of isolation of S. aureus and MRSA was seen among 480 in-patients (47.1% and 32.7% respectively) compared with 256 HCWs (32.8% and 19.1% respectively). Significant resistance (P<0.05) to clindamycin, erythromycin, ciprofloxacin, tetracycline and co-trimoxazole was seen in MRSA isolates recovered from in-patients. MRSA isolates had higher cMLSB and iMLSB resistance. Years of service and level of education in HCWs were significantly associated with MRSA carriage in them. Conclusion: Nasal-carriage of S. aureus and MRSA is common in HCWs and in-patients in our hospital. Apart from periodic screening for MRSA carriage, strict adherence to existing infection control guidelines is mandatory.
Authors and Affiliations
Peer Maroof, Reyaz Nasir, Nargis Bali, Anjum Farhana, Maria Amin, Farhath Kanth
Keywords
Related Articles
- EP ID EP350820
- DOI 10.9734/BMRJ/2016/23800
- Views 104
- Downloads 0
Molecular Detection of Antibiotic Resistance of Helicobacter pylori from Gastric Biopsies in Abidjan (Côte d'Ivoire)
Aims: To determine the genes of resistance to amoxicillin, clarithromycin and metronidazole of Helicobacter pylori in gastric biopsies in Côte d'Ivoire. Place and Duration: The study was performed at the department of g...
Streptomyces nobilis C51 Suppresses Gray Mold Caused by Botrytis cinerea in Tomato
This study sought to develop a biological control agent against gray mold disease caused by Botrytis cinerea in tomato using a strain of Streptomyces, which showed significant antagonistic activity against B. cinerea. Su...
Antibiotic-Resistant Enterococcus faecalis Isolated from Food Canteens in Osun States, Nigeria
Enterococci have continued to attract considerable importance and attention as pathogens of public health concern both in the hospital and environmental settings. Therefore epidemiological studies of these organisms are...
Proteases Production by a Bacterial Isolate Bacillus amyloliquefaciens 35s Obtained from Soil of the Nile Delta of Egypt
Aims: The present work was designed to investigate the production of proteases from an Egyptian bacterial isolate. Study Design: Samples were collected from soil, water and food, and screened for the isolation of protea...
Activity Guided Fractionation with Antimicrobial Evaluation of Pergularia tomentosa L. (Asclepiadacea) Whole Plant
This research work aimed to present the activity guided fractionation with antimicrobial evaluation from both crude extract and various fractions obtained from Pergularia tomentosa L. whole plant. The P. tomentosa L. who...