Statins Can Reduce the Likelihood of Patients Developing Acute Periapical Abscesses

Journal Title: Journal of Dental Health and Oral Research - Year 2025, Vol 6, Issue 1

Abstract

Background: The aim of this study was to assess the impact of statins on patients with diabetes and smoking comorbidities who subsequently developed Acute Periapical Abscesses (APAs) by reviewing nearly 1.8 million patient medical records. Methodology: This study investigated the effect of statins on APA incidence in patients by reviewing nearly 1.8 million patient medical records. Results: The odds of developing APAs were significantly reduced for patients taking certain statins. When adjusting for diabetes comorbidity, all statins studied reduced the OR significantly. When adjusting for smoking comorbidity, atorvastatin and pravastatin reduced the odds of developing APAs by almost 2 times (OR 1.22, p<0.0001) and (OR 1.27, p<0.0001), respectively. Conclusion: These findings suggest that statins, beyond their lipid-lowering properties, may offer additional health benefits, including a reduced risk of APAs.

Authors and Affiliations

Joseph Katz1, Ilan Rotstein2*, Franklin Garcia-Godoy3

Keywords

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  • EP ID EP759980
  • DOI https://doi.org/10.46889/JDHOR.2025.6105
  • Views 25
  • Downloads 0

How To Cite

Joseph Katz1, Ilan Rotstein2*, Franklin Garcia-Godoy3 (2025). Statins Can Reduce the Likelihood of Patients Developing Acute Periapical Abscesses. Journal of Dental Health and Oral Research, 6(1), -. https://www.europub.co.uk/articles/-A-759980