STERILE ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION OF BEVACIZUMAB FROM A SINGLE VIAL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 16
Abstract
PURPOSE: To study the occurrence of sterile endophthalmitis in patients undergoing intravitreal Bevacizumab for various indications. METHODS: A retrospective analysis of case records of patients who developed intense anterior and posterior segment reaction after intravitreal bevacizumab was done in detail. RESULTS: Six of the twenty six patients (23%) developed sterile endophthalmitis. There was no growth in repeated culture of aqueous or vitreous samples. All patients showed precipitation of drug in vitreous with resolution of symptoms after 8 weeks of intensive steroid treatment. CONCLUSION: Intravitreal bevacizumab can cause sterile endophthalmitis though it is a diagnosis of exclusion. In view of many complications a larger clinical trial of intra vitreal bevacizumab is the need of the hour to justify its use.
Authors and Affiliations
Kalpana B. N, Mohammed Sadiqulla
Keywords
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- EP ID EP227187
- DOI 10.18410/jebmh/2015/344
- Views 99
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