Study of Alterations in Liver Function Tests Following Laparoscopic Surgery
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Laparoscopic surgery has revolutionized the field of general surgery and has gained worldwide popularity and acceptance. However as it became more prevalent new concerns arose regarding the adverse effects of carbon dioxide pneumoperitoneum and increased intra-abdominal pressure during laparoscopic procedures. This is a prospective study, where blood samples were collected from 60 inpatients, undergoing various laparoscopic procedures, preoperatively once and post operatively on days 1 and 3. They were tested for liver function by assessing levels of serum bilirubin, serum alanine amino transferase (ALT), serum aspartateaminotransferase (AST) and serum alkaline phosphatase (ALP). The level of serum AST, ALT, bilirubin and alkaline phosphatase increased significantly during the immediate post-operative period. Doubling of pre-op values of AST was seen in 28.3% and of ALT was seen in 25%. By the 3rd post-operative day, levels of AST, ALT, bilirubin and alkaline phosphatase returned to near pre-operative values. Therefore, transient elevation of hepatic enzymes occurred after all types of laparoscopic procedures. This transient rise showed no apparent clinical implication in most patients. However in those with hepatic insufficiency, care should be taken before deciding to perform laparoscopic surgery.
Authors and Affiliations
Dr P Rama Rao, Dr Shruti Kongara, Dr Y Snigdha, Dr K. A. S. S. N. Kalyan
Keywords
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- EP ID EP599013
- DOI 10.9790/0853-1603084854.
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