Study of amplitude of accommodation in patient with Human Immunodeficiency Virus infection on Anti Retro virus Treatment
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 6
Abstract
Introduction: Human Immunodeficiency Virus [HIV] is known to cause premature ageing leading to reduction in amplitude of accommodation It is associated with many other ocular and systemic diseases. Aim: The primary objective was to find out if HIV-positive patients on Anti Retroviral Treatment [ART] have significantly reduced amplitude of accommodation compared with controls. The secondary objective was to investigate accommodative impairment in relation to factors such as age, CD4 count and current antiretroviral treatments. Method: It was a cross sectional, open and prospective single center study in a tertiary care hospital in Western Maharashtra. It involved 200 HIV-positive patients on ART aged from 35 years to 45years with no previous history of eye problems and 200 age-matched controls. Results: Blur reported by HIV patients using Royal Air Force [RAF] ruler for 35- 39 years age group was 27.94% [19/68] while for control group it was 2.08%[2/96], [p value <0.001]Reduced amplitude of accommodation below age expected norms was also observed. For age group 40-45 years , reduction in amplitude of accommodation found for HIV patients and control was 92.42% and 95.09% respectively, [p Value <0.001]Accommodation failure was not related to CD4 count or current ART being used. Conclusion: This study has identified accommodative failure in a significant proportion of HIV-positive patients on ART aged between 35and 45years. This problem may be under-recognized. The need for near correction for the pre presbyopic age is often overlooked. Accommodation failure was not related to CD4 count or current ART being used.
Authors and Affiliations
Neeta Mishra
Keywords
Related Articles
- EP ID EP288148
- DOI -
- Views 72
- Downloads 0
Aetiologies of Acute Gastroenteritis in Hospitalized Children
Introduction: Diarrheal disease and acute gastroenteritis is one of the important cause of morbidity and mortality among young children in developing countries. Most of the clinical burden of acute gastroenteritis (AGE)...
Correlation of Serum Magnesium Levels with Microvascular Complications among Type 2 Diabetes patients in South India
Background: Hypomagnesemia has been found to be associated with unfavorable effects on glucose homeostasis and insulin sensitivity in Type 2 Diabetes Mellitus (DM). If a relationship between levels of serum magnesium and...
A Prospective Study of Fixation of Lateral end Clavicle with Tension band Wiring
Background: Displaced lateral end clavicle fractures have high incidence of delayed union or non-union, hence several authors suggested operative management for these fracture. Adequate reduction and minimal soft tissue...
A Study to Find out the Effectiveness of Taping Versus Semi rigid Bracing in Ankle Sprain
BACKGROUND: Ankle sprain is one of the most common musculoskeletal injuries, accounting for an estimated 600.000 persons per year. Preventive interventions such as taping and bracing are thought to decrease ankle sprain...
Prevalence of Different Types of Urinary Incontinence and their Association with Age and Parity
Introduction: Urinary incontinence (UI) is one of the most common diseases in the world, occurring majorly in females. One out of five women in the world suffers from disease. Based on pathophysiology urinary incontinenc...