Study of Cardiovascular Manifestations of Rheumatoid Arthritis and Correlation with Disease Duration and Severity
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Aims and objectives: Rheumatoid arthritis is a systemic chronic inflammatory disorder of unknown etiology that primarily involves synovial joint, and secondarily involves various organ systems. Involvement of cardiovascular system is well known but the disease is mainly subclinical. The study was conducted to see the prevalence of various cardiovascular manifestations in rheumatoid arthritis and correlate them with disease duration and severity. Material and methods:In this cross-sectional study, 60 patients of rheumatoid arthritis attending outpatient and inpatient department at Rajindra Hospital and Government Medical College, Patiala were included. They were thoroughly investigated for cardiovascular abnormalities. Results:The mean age of the patients was 45.37 ± 10.96 years. Females outnumbered the males in this study. The mean duration of the disease was 4.62±2.49 years. Of all patients with cardiovascular abnormalities, 40% patients (24 cases) had echocardiographic abnormality, 40% had hypertension and 11.67% had ECG abnormality. The most common echocardiographic abnormality was LV diastolic dysfunction, followed by pericardial effusion.There was significant correlation of these manifestations with disease duration and severity. Conclusion: The cardiovascular abnormalities showed a direct relationship with the increasing duration as well as severity of the disease. Hence, it is important to screen the patients of rheumatoid arthritis for these abnormalities so that early identification and treatment can be provided.
Authors and Affiliations
Dr. Raminderpal Singh, Dr. Chamanjot Kaur, Dr. Preetkanwal Sibia, Dr. Baldeep Singh4, Dr. Ankur Chaudhary5
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