Study of Correlation of Cord Blood Bilirubin with Neonatal Hyperbilirubinemia
Journal Title: MVP Journal of Medical Sciences - Year 2016, Vol 3, Issue 1
Abstract
Introduction: Neonatal Hyperbilirubinemia (NH) is a universal problem affecting nearly 60% of term and 80% of preterm neonates during first week of life. Early discharge of healthy term newborns is a common practice because of medical, social and economic constraints. Insignificant number (6.5%) of babies, NH is a cause for readmission. The present study was conducted to correlate the Cord Blood Bilirubin (CBB) level with subsequent NH. Methods: Study was performed at the Department of Pediatrics in a Medical College Hospital and Research Centre. Intramurally delivered, 113 Healthy full-term newborns during 1-year period were prospectively enrolled. CBB was estimated. Serum Bilirubin estimation was done at 48 hours and 5 day of age and later if required. Results: Significant NH in our study is 3.5%. Mean total bilirubin on second postnatal day was 10.58 mg/dl and on fifth post natal day was 10.81 mg/dl. Using CBB level of ≥3 mg/dl as a cut-off, NH can be predicted with sensitivity of 100%, specificity of 98.17%, positive predictive value of 66.67% and negative predictive value of 100%. Conclusion: A 100% Negative Predictive Value in the present study suggests that in Healthy Term babies (without RH and ABO incompatibility with Cord Blood Bilirubin ≤3mg/dl) cord serum bilirubin can help to identify those newborns who are unlikely to require further evaluation and intervention. These newborns can be discharged with assurance to Parents. Babies with CBB level ≥3mg/dl should be followed more frequently.
Authors and Affiliations
Nilesh Ahire, Ravindra Sonawane, Rajendra Gaikwad, Suhas Patil, Tushar Sonawane
Keywords
Related Articles
- EP ID EP434379
- DOI 10.18311/mvpjms/2016/v3i1/739
- Views 148
- Downloads 0
Cytomorphologic Analysis of Body Fluids
Background: Many etiologies result in development of effusions in the serous cavities. Of these pleural, peritoneal, pericardial fluids and cerebrospinal fluid are the most common. Cytologic study is done to diagnose dis...
Pilomatrixoma of the Thigh - A Case Report
Pilomatrixoma is a benign skin tumor derived from hair follicle matrix cells. They typically present as a superficial, firm, solitary, slow-growing, painless mass in the dermis. Pilomatricomas are frequently misdiagnosed...
Fibrin Glue Vs Vicryl (10-0) Suture in Limbo Conjunctival Autograft in the Management of Primary Pterygium : A Prospective Comparative Study
Background: Pterygium is a wing shaped fibrovascular tissues proliferation from the conjunctiva on to the cornea. There is no satisfactory treatment for pterygium available yet. Among the available treatments, surgical t...
Study of Serum Alkaline Phosphatase Levels among Psoriasis Patients and Comparative Group in Tertiary Care Institute
Background: Psoriasis is a chronic relapsing autoimmune skin disease of unknown etiology, characterised by complex alterations in epidermal growth and differentiation. Oxidative stress is a known risk factor for exacerba...
A Case of Pleomorphic Variant of Embryonal Rhabdomyosarcoma in Skeletal Muscle - A Rare Case Report
Embryonal Rhabdomyosarcoma (ERMS) is a malignant soft tissue tumour with phenotypical and biological features of embryonic skeletal muscle cells. It is rare in skeletal musculature of extremities and its pleomorphic vari...