Study of First Line Antibiotics in Lower Respiratory Tract Infections in Children

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2

Abstract

Lower respiratory infections are the most common infection in children. Antibiotics are the most commonly prescribed drug for children. Based on this a prospective observational study performed in Department of Paediatrics, at RMMCH, Annamalai University, TamilNadu, period of study 6 months; Between November 2015 and April 2016. Totally 100 patients in paediatrics ward with LRTI who satisfy the inclusion and exclusion criteria were enrolled. The objective of this study is to study the prescribing pattern of first line antibiotics in lower respiratory tract infections in children, to document the adverse drug reactions(if any), to study the cost effective treatment pattern. Our study shows that male patients and patients of age group of 4months -5years are mostly affected with LRTI. Bronchiolitis (34%) was the major incidence in children who admitted with LRTI. The major category of first line antibiotic prescribed was penicillin (60%) followed by cephalosporins, among this amoxicillin-clavulanic acid was the most common antibiotic prescribed followed by cefotaxime + amikacin. Majority of drugs were given by intravenous route of administration. Single antibiotic therapy was commonly used. A total of 6 ADRs were found in which nausea and vomiting, redness and swelling at injection sites were common. Ampicillin + gentamicin were the cost effective treatment pattern.

Authors and Affiliations

*Basim Poozhithara, Lakshmi Sravani. B, P. Mahendra varman1, S. Nathiya2

Keywords

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  • EP ID EP390281
  • DOI 10.9790/3008-1204064755
  • Views 80
  • Downloads 0

How To Cite

*Basim Poozhithara, Lakshmi Sravani. B, P. Mahendra varman1, S. Nathiya2 (2017). Study of First Line Antibiotics in Lower Respiratory Tract Infections in Children. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 17(2), 47-55. https://www.europub.co.uk/articles/-A-390281