STUDY OF PREVALENCE OF GRANULOMATOUS LYMPHADENITIS IN INDIVIDUALS AFFECTED WITH HIV INFECTION
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 82
Abstract
BACKGROUND Prevalence of Granulomatous lymphadenitis in human immune deficiency virus infection is increasing drastically in developing countries, particularly in India. In the present study, an attempt has been made to find an association of Granulomatous lymphadenitis in human immune deficiency virus infection in humans. The aim of this study is to correlate the FNAC finding with clinical, radiological and morphological patterns like correlation with findings and the CD4 count, relation of Mantoux to lymph nodes and relation with x-ray findings. MATERIALS AND METHODS A descriptive study done in 100 adult patients, aimed to study the prevalence of tuberculous lymphadenitis by cytological patterns in lymph nodes of HIV sero-positive patients by collecting and studying material through FNAC and clinical importance by Mantoux and x-ray findings. Patients attending Government General Hospital, ACSR GMC, Nellore who was not on ATT or ART were chosen for the study. RESULTS Various lesions were observed in this study. Granulomatous lymphadenitis was observed in 74 cases, reactive lymphadenitis was seen in 22 cases and acute suppurative lymphadenitis was seen in 3 cases. One case has shown secondary deposits of squamous cell carcinoma. CONCLUSION FNAC is a relatively inexpensive initial investigative technique important for assessing the cause of lymphadenopathy in HIV patients; allows a rapid diagnosis obviating the need for surgery and enabling swift treatment to be undertaken where necessary. Universal safety precautions must be strictly followed. The method is accurate, cost effective and acceptable to patients. TB is the major opportunistic infection, which could be detected in both symptomatic and asymptomatic individuals and even in tiny nodes. There was strong association with Mantoux and x-ray for diagnosing Granulomatous lesions
Authors and Affiliations
Dana Srinivasa Rao, Varikuti Aparna, Beenaboina Venkata Ramana Murthy, Bellamkonda Gopi Krishna, Neeraja Neeraja
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