Study of retinal nerve fiber layer and foveal thickness in amblyopia
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2017, Vol 3, Issue 1
Abstract
Aim: To measure and compare the retinal nerve fiber layer (RNFL) and foveal thickness of normal and amblyopic eyes in unilateral amblyopia. Material and Methods: This was a prospective, observational cross-sectional study conducted over a period of one year, after approval from the Institutional ethical committee. Children presenting to the pediatric ophthalmology clinic with a diagnosis of unilateral amblyopia due to anisometropia or strabismus or both were included. All children underwent clinical examination including BCVA, anterior and posterior segment examination and squint workup in cases of strabismus. Retinal nerve fiber layer (RNFL) and foveal thickness were measured in amblyopic as well as normal eye by Optovue RTvue 100 Fourier domain OCT. Statistics: The Student t-test was used to compare the RNFL and foveal thickness in the normal and amblyopic eye. Results: The study included 31 children out of which 16 (51.62%) were male and 15 (48.38%) female. Mean age of presentation was 11.29±3.06 years. There were 58.06% with anisometropic, 22.58% with strabismic and 19.36% subjects with mixed amblyopia. The mean foveal thickness of normal eyes was 254.64±35.57 μm whereas that of corresponding fellow amblyopic eyes was 271.29±28.08 μm with a p-value of 0.045. The mean RNFL was thicker in the normal eyes (111.06±17.63 μm) than the fellow amblyopic eye (108.80±23.50 μm) but this difference was not statistically significant (p=0.670). Conclusion: Foveal thickness was found significantly more in the amblyopic eye than fellow normal eye whereas the RNFL thickness showed no statistically significant difference between the two groups.
Authors and Affiliations
Shivam Sood, Amit Maitreya, Renu Dhasmana
Keywords
Related Articles
- EP ID EP298355
- DOI 10.18231/2395-1451.2017.0018
- Views 106
- Downloads 0
Evolving view of toric IOL
Incidence of ocular manifestations in HIV infected patients: a study in a teaching hospital in Telangana
Introduction: Ocular manifestations of human immunodeficiency virus (HIV) infection are common. The aim of this study was to assess the prevalence of the ophthalmic manifestations observed in AIDS patients. Materials and...
A study on the angle of anterior chamber in relation to duration of diabetes mellitus and stages of diabetic retinopathy
Introduction: Persons with diabetes are more prone to develop shallow anterior chamber than the non diabetics. Decrease in Anterior chamber depth may lead to primary angle closure glaucoma (PACG). Our objective is to mea...
To compare the Gonioscopic changes in the angle after conventional ECCE with PC IOL implantation and Small Incision Cataract Surgery with PCIOL
Introduction: To observe and compare the Gonioscopic changes in the angle after · Conventional ECCE with PC IOL implantation · Manual Small incision Cataract Surgery with PCIOL implantation An attempt has...
Retinopathy of prematurity: Incidence and risk factor
With the advent of new technologies in neonatal health care the mortality rate of infants have gone down drastically and has resulted in spike of ROP and its severityAim To study risk factors for Retinopathy of prematuri...