STUDY OF THE BASELINE WIDAL TITRES AMONG HEALTHY INDIVIDUALS OF RURAL POPULATION IN PUDUCHERRY
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2015, Vol 4, Issue 2
Abstract
Background: Enteric fever is endemic in developing countries like India. Widal test in a single serum sample is often the only test relied upon for laboratory diagnosis. The test is considered positive if the antibody titres are higher than the cut - off value in a single test or a rising titre in paired sera. But normal baseline titres in healthy population and cutoff values have not been established in our area. So the aim of our study was to determine the base line titres of antibodies among apparently healthy populations and to define the significant titres of widal test. Materials and Methods: Samples were initially screened by Widal slide agglutination test and further confirmed by the Quantitative tube agglutination test. Results: Among the 500 samples from apparently healthy individuals, 260 samples were positive for agglutinins. 141 were positive for ‘O’ agglutinin and 163 were positive for ‘H’ agglutinin of Salmonella typhi. Among 141 samples, 30 showed agglutination up to 1in 20 titre, 100 up to 1in 40 and 25 (4.8%) up to 1in 80. Among 163 samples, 18 showed a titre of 1 in 20, 120 showed a titre of 1 in 40 and 21(4.2%) up to 1 in 80. Conclusion: When a single widal titre is used for the diagnosis of enteric fever in our locality, it will be more appropriate to change the currently used cutoff levels against S.typhi to ≥ 1 in 160 for anti-O and ‘H’ agglutinins remains the same of ≥ 1 in 160.
Authors and Affiliations
Jeyakumari D| Department of Microbiology, Tagore Medical College & Hospital, Chennai, Tamil Nadu, India, Corresponding author email: karailabscuddalore@yahoo.co.in, Jaberlin Sneha AJ| Department of Microbiology, Sri Manakula Vinayagar Medical College & Hospital, Puducherry, India, Gopal R| Department of Microbiology, Sri Manakula Vinayagar Medical College & Hospital, Puducherry, India
Keywords
Related Articles
- EP ID EP11394
- DOI 10.5958/2319-5886.2015.00060.0
- Views 240
- Downloads 11
Prognostic Importance of Sarcopenia in Patients with Clear Cell Carcinoma
Background: Sarcopenia has recently been identifed as a prognostic factor for various types of cancers. Our aim in this study was to investigate the relationship between sarcopenia and the clinical course and overall su...
Effects of Intrathecal Clonidine on Spinal Analgesia during Elective Cesarean Delivery: A Randomized Double Blind Clinical Trial
In order To investigate the effect of addition of clonidine to lidocaine on duration of spinal analgesia and need for postoperative analgesics after Caesarean section delivery, this randomized case-controlled double-bli...
A rare case of Mounier-Kuhn syndrome with bronchial asthma
Tracheobronchomegaly(Mounier–Kuhn syndrome) is dilatation of the trachea and major bronchi because of atrophy or absence of elastic fibers and smooth muscle cells .Patients presenting to primary care physician with l...
TO STUDY THE EFFECT OF THE BODY MASS INDEX AND WAIST HIP RATIO ON BLOOD PRESSURE IN PRE- AND POST-MENOPAUSAL WOMEN
Background: Menopause is the transient period of declined ovarian activity and decreased oestrogen level associated with increased chances of obesity and increased comorbidities like hypertension, hypercholestrelemia, i...
Examining the Relationship between Communication Patterns of Source Family and Self-Consciousness with Defensive Styles of Discordant Couples
Research has shown the relationship between communication patterns of source family with defensive styles of discordant couples. For this reason, the present research has examined the relationship between communication...