STUDY OF THYROID PROFILE AND PROLACTIN IN INFERTILE WOMEN: A CASE CONTROL STUDY.
Journal Title: IJAR-Indian Journal of Applied Research - Year 2018, Vol 8, Issue 9
Abstract
Background: In Indian societies womanhood is defined through motherhood and infertile women usually carry the blame for the couple’s inability to conceive. In many cases, the childless woman is made to feel inferior and may be abused or even tortured by the family. In India estimated infertility to be in the range of 4-6 %. Among all causes of female infertility, ovulatory dysfunction due to endocrinal abnormalities like, thyroid dysfunction and hyperprolactinemia are most common and most reversible (treatable) cause. Method: Hospital based study of thyroid dysfunction and prolactin level in infertile women a case control study. Hundred consecutive infertilewomen from Infertility clinic of OBGY department was enrolled and equal number of fertile women of reproductive age group, controls were taken from OBGY OPD. Result: Thyroid dysfunction (OR = 4.85, 95% CI = 2.39 - 9.81, P = 0.0001), Hyperprolactinemia (OR = 4.25, 95% CI = 1.82 - 9.92, P = 0.0004), Menstrual abnormalities (OR = 4.13, 95% CI = 2.12 - 8.02, P = 0.0001) were significantly associated with infertility. Difference between mean TSH values and mean prolactin level in cases and controls were found to be highly significant (p=0.0001). Conclusion: Thyroid dysfunction, hyperprolactinemia and menstrual abnormalities were significantly higher in infertile women as compared to the fertile women. There was weak positive correlation between hypothyroidism and hyperprolactinemia in infertile women. Routine screening of infertile women will facilitate early diagnosis and treatment of these two disorders which will certainly help in restoring fertility in these women
Authors and Affiliations
Dr Suresh Ghangale, Dr Amol Sonare, Dr Sanjivani Jadhao, Dr Ashok Jadhao
Keywords
Related Articles
- EP ID EP391648
- DOI -
- Views 76
- Downloads 0
EVALUATING THE ROLE OF LIFE STYLE MODIFICATIONS IN THE PATHOGENESIS OF SHEETAPITTA~URTICARIA
Life style diseases are defined as diseases linked with the way people live their life. It includes daily routine of people comprising their food habits, sleep pattern, other activities, emotional set up etc. keeping thi...
Farm Mechanisation is the Need of the Time: It’s Picking Up in Odisha Led by Youth
Agricultural land area is not increasing, but the demand for food is ever increasing due to population growth. To meet the demand of increasing population for food and for income security increase in crop productivity is...
Right Iliac Fossa Mass : A Surgical Dilemma
Right iliac fossa mass is a surgical dilemma a surgeon encounters in surgical practice arriving to diagnosis of which is dificult. Various conditions presenting as lump includes spectrum of diseases like appenicular lump...
MORPHOMETRIC STUDY OF PLACENTA IN NORMAL AND HYPERTENSIVE PREGNANCIES
Background – Placenta is a vital organ which is directly related to maintaince of pregnancy and normal fetal growth. Fetal outcome is adversely affected by changes in placenta due to hypertension complicating pregnancy....
Effectiveness of Guided Imagery on Burnout Syndrome Among Staff Nurses Working in Dhiraj General Hospital at Piparia, Vadodara
Background: The term "burnout" is related to a situation arising increasingly more often among the professionals performing their duties by way of a long-term, direct, people-to-people relationship, which includes all he...