Study on the progress of HIV typing methods
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 7
Abstract
As a retrovirus with high recombination and mutation rateï¼ HIV targets CD4+ T lymphocytesï¼ causing damage to the body's immune system and eventually leading to severe immune function defects. Different subtypes of the HIV virus exhibit significant sequence differences in their structural and regulatory genesï¼ and this diversity is closely related to etiologyï¼ transmissionï¼ diagnosisï¼ drug therapyï¼ disease progressionï¼ and vaccine development. As a country with the largest number of HIV subtypesï¼ rapid and accurate typing of the HIV virus holds great significance for China's efforts in disease prevention and control. This study provides a comprehensive reveiw of domestic and international HIV genotyping methodsï¼ and summarizes the clinical significance of different subtypes in order to provide reference for further research.
Authors and Affiliations
LIN Qianru,LIN Yi,ZHONG Ping,SHEN Xin,
Keywords
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