Synthesis and Antimicrobial Activity of 5-{4'-[(4"-aryl)- -3"-cyano 2"-ethoxy pyridine-6"- yl] phenyl carbamido}-dibenz [b,f] azepines derivatives
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2016, Vol 4, Issue 1
Abstract
The titled compounds (4a-4k) have been synthesized by the condensation of 5-{4'-[(3"-aryl)-2"- Propene-1"-one]-Phenyl carbamido}-dibenz [b,f] azepines with malononitrile and Sodium ethoxide. The biological activities of these compounds have been determined against various Gram +ve, Gram –ve bacteria and fungi. The constitutions of the products are supported by IR, 1 H NMR, Mass spectra and elemental analysis.
Authors and Affiliations
Ramesh K. Kanpariya
Keywords
Related Articles
- EP ID EP31513
- DOI -
- Views 360
- Downloads 1
Importance of Agni and its Impact on Human Body
Ayurveda is the ancient Indian system of life sciences and Medicine, its historicity going back to the Vedas. Its classical knowledge and practice is based on its own physics and biology, its unique pronature holistic...
Polymeric systems as controlled release drug products: A review
The use of various new techniques and therapeutic systems to obtain a controlled drug release in microbial infections is a more and more exploited approach in the modern pharmaceutical technology. Growing interest in thi...
A view over Saama Rasa Dhatu and its effects on body
Ayurveda is the basic and the most ancient science of life in which it has been said that human body is chiefly composed of doshas, dhatus and malas. So, the basic step for the maintenance of health and for treating th...
The Prevalence of Hepatitis B among Medical Students, Majmaah University, Kingdom of Saudi Arabia
Background: Medical students in the course of their clinical work are at risk of acquiring hepatitis B virus (HBV) infection or transmitting it to their patients. HBV immunization for medical students in Saudi Arabia is...
In-Vitro Cytotoxicity Study of Some Indigenous Medicinal Plants on Vero Cell Line
The ethno botany and ubiquitous plants as a source of medicine has been an important component of the health care system providing a rich resource for natural drug research and development. Natural products from medici...