SYNTHESIS AND BIOLOGICAL STUDIES OF CHERIMOLACYCLOPEPTIDE E AND ITS N- METHYLATED ANALOG
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 12
Abstract
The N-methyl derivative of Cherimolacyclopeptide E cyclo[Phe-(Dimethyl)Tyr-Pro-Gly-Leu-Gly] was synthesized using solution phase peptide synthesis. The synthesized compound was characterized by spectral data and was evaluated for anthelmintic and insecticidal activities. The compound exhibited potent anthelmintic activity as compared to the standard drug mebendazole.
Authors and Affiliations
M Himaja , Rajan Siji , A. A Karigar, M. V Ramana
Keywords
Related Articles
- EP ID EP160992
- DOI -
- Views 112
- Downloads 0
LONG-ACTING BETA2-AGONISTS VERSUS LEUKOTRIENE RECEPTOR ANTAGONIST AS ADD-ON THERAPY TO CORTICOSTEROIDS FOR CHRONIC ASTHMA MANAGEMENT IN PATIENTS OF KARACHI, PAKISTAN
Asthmatic patients are usually maintained with inhaled corticosteroids but if symptoms are appearing we need to manage asthma with add on therapy either with LABA or leukotriene receptor antagonist. To estimate which mai...
EFFECT OF ETHYL ACETATE EXTRACT OF BLACK TEA ON CARDIOVASCULAR COMPLICATIONS ASSOCIATED WITH STREPTOZOTOCIN DIABETIC RATS
Diabetes mellitus (DM) is associated with an increased incidence of cardiovascular events and microvascular complications. These complications contribute to the morbidity and mortality associated with the disease. There...
REVIEW ON ALBIZIA LEBBECK A POTENT HERBAL DRUG
Herbs and herbal drugs have created interest among the people by the clinically proven effects like immunomodulatios, adaptogenic and antimutagenic. Also the overuse of synthetic drug, which results in higher incidence o...
STUDIES ON COMPRESSION AND DRUG RELEASE CHARACTERISTICS OF XANTHIUM GUM PELLETS OF DIFFERENT COMPOSITIONS
The filler used in preparation of pellets affects physical properties, compression and drug release rates. The present investigation was aimed to develop a sustained drug delivery system for a short half life drug, Simva...
FIELD TEST FOR THE DETECTION OF PHYTOSTEROLS
There are some standard tests which are used for the detection of phytosterols. Field test is quick and efficient method. It is also advantageous because of the use of less quantity plant material and chemical. A small p...