Synthesis and screening for biological potential of some substituted chalcones
Journal Title: International Journal of Pharmaceutical Chemistry and Analysis - Year 2018, Vol 5, Issue 2
Abstract
The present paper describes the synthesis and antibacterial as well as antioxidant activity of new chalcone derivatives derived from pchloroacetopheneone In the present work the reaction of pchloroacetophenone with different substituted aromatic aldehyde The newly synthesized chalcones AD were analysed by their spectral data TLC IR UV and melting point These newly synthesized compounds were evaluated for invitro antioxidant activity by Diphenyl Picryl Hydrazine DPPH model using ascorbic acid as standard and for antimicrobial activity by Cup Plate method on gram positive and gram negative bacterial strain using amoxicillin as standard Keywords Chalcone Antimicrobial Antioxidant Pchloroacetophenone Aromatic aldehyde
Authors and Affiliations
K. R. Gupta, S. Badole, J. K. Gupta, S. V. Singh
Keywords
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- EP ID EP481440
- DOI 10.18231/2394-2797.2018.0013
- Views 75
- Downloads 0
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