Synthesis, Characterization and Antimicrobial Studies of Schiff base Derived from Salicyldehyde and 2,4-dinitrophenyl hydrazine and its Metal (II) Complexes
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 9
Abstract
Schiff base ligand derived from salicylaldehyde and 2,4-dinitrophenylhydrazine were synthesized. Cu(II) and Zn(II) complexes (CuL2 and ZnL2) were synthesized. The compound were characterized on the basis of melting point/decomposition temperature, solubility, molar conductance, magnetic susceptibility infrared analysis and UV visible spectrophotometry. The complexes have been found to be 1:2 (Metal-Ligand) ratio. All the complexes have low molar conductance values, between (6.39-6.59) indicating non-electrolytic nature. The synthesized ligand and its metal (II) complexes were screened for antibacterial activity against five bacterial isolates (Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Pseudomonas aureginosa and Staphylococcus aureus) and three fungal isolate (Fusarium solani, Aspergillus fumigate and Candida albicans) using well method. The results revealed that the complexes show more activity against the microorganisms compared to the Schiff base.
Authors and Affiliations
H. Mukhtar, U. Sani, M. H. Shagal, J. I. Joseph
Keywords
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- EP ID EP414405
- DOI 10.9790/5736-1109014953.
- Views 183
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