SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF SOME d10 METAL COMPLEXES WITH A NEW MANNICH BASE N-[(DIPHENYLAMINO) METHYL] ACETAMIDE
Journal Title: Asian J of Pharm Sci & Tech - Year 2015, Vol 5, Issue 2
Abstract
ABSTRACT The complexes of ZnII, CdII and HgII with N-[(Diphenylamino)methyl]acetamide (DPAMAce) have been synthesized and characterized. The resulting complexes were characterized by elemental analysis, conductivity measurements, IR and 1H NMR spectral studies. The Mannich base ligand acts as a neutral bidentate, coordinating through the carbonyl oxygen and azomethine nitrogen atoms. The complexes are non-electrolytic in DMSO. The presence of the coordinated water molecules in all the complexes was indicated by IR spectra of the complexes. From the analytical and spectral data, all the four complexes exhibit octahedral geometry. The antimicrobial activities of ligand and their complexes were screened by disc diffusion method. It is found that the metal complexes have higher antimicrobial activity than the free ligand. Key words: Mannich base, Condensation, Metal complexes, Physicochemical techniques
Authors and Affiliations
L. Muruganandam*, S. Selvam and V. Kanimozhi
Keywords
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