SYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL ACTIVITY OF 2,6-DITERTIARY BUTYL-1,4-BENZOQUINONE HYDRAZONES  

Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 8

Abstract

Four 2,6-di-tert-butyl-1,4-benzoquinone hydrazones have been synthesized viz. A1, A2, A3 and A4. The purity was checked using HPLC. These compounds were characterized by FTIR and H1-NMR and they shows a prominent absorption of -(C=N-) in FTIR. It also shows a common peak of oleifinic proton at 6.50 Hz. These hydrazones were tested for their antimicrobial activity against Gram +ve and Gram –ve bacteria. A3 was found to be active at a minimum concentration of 50 μg•mL–1 where as A2 was inactive. 

Authors and Affiliations

Anees Pangal, Khursheed Ahmed, Sajid Shaikh

Keywords

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  • EP ID EP93500
  • DOI 10.7897/2230-8407.04834
  • Views 101
  • Downloads 0

How To Cite

Anees Pangal, Khursheed Ahmed, Sajid Shaikh (2013). SYNTHESIS, CHARACTERIZATION AND STUDY OF ANTIMICROBIAL ACTIVITY OF 2,6-DITERTIARY BUTYL-1,4-BENZOQUINONE HYDRAZONES  . International Research Journal of Pharmacy (IRJP), 4(8), 172-176. https://www.europub.co.uk/articles/-A-93500