Synthesis, characterization, antimicrobial studies and computational studies of a new Shciff‘s base ligand derived from 3-aminocoumarin and its metal complexes
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 3
Abstract
The novel Schiff’s base ligand (OCYMB) 3 synthesized by the condensation of o-phthalaldehyde and 3- aminocoumarin. The nature bonding and geometry of the transition metal complexes as well as ligand have been deduced from elemental analysis, mass, NMR, IR &ESR. These metal complexes containing Mn(II), Co(II), Ni(II), Cu(II) & Zn(II) complexes are found to have octahedral and Pd(II) complex shown square planar geometry. The ligand has tetradentate which co-ordinate through N-atom of azomethine group and Oatom of oxo group of 3-aminocoumarin. The geometry of ligand and its metal complexes were evaluated by using computational studies and also studied their antibacterial activity against gram +ve and gram –Ve bacteria.
Authors and Affiliations
Dr. Kotte Shylaja
Keywords
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