Synthesis, Charecterization And Antibacterial Activity of Some Novel Chalcones And Its Derivatives
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 8
Abstract
Chalcones, (E)-N-(4-(4,6-dichloro-1,3,5 –triazin-2-ylamino) phenyl)-3-(4-methoxyphenyl) acrylamide (4a-c) have been prepared according to Claisen-Schmidt condensation. Further these chalcones (4a-c) on reaction with malononitrile affords cyanopyridines (5a-c) and on reaction with hydrazine hydrate affords pyrazole (6a-c) respectively. The constitutions of newly synthesised compounds have been characterized on the basis of their IR and 1H NMR, 13C NMR spectral data.These synthesized compounds have been screened for their antibacterial activity.
Authors and Affiliations
M. Thamizhthendral, S. Syed Shafi
Keywords
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- EP ID EP414378
- DOI 10.9790/5736-1108012732.
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