Synthesis, Structure Elucidation and Biological Studies of 2-{[5-(4-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-arylacetamide derivatives

Journal Title: Journal of Biological and chemical Chronicles - Year 2018, Vol 4, Issue 1

Abstract

A series of ten derivatives of titled compounds was designed and synthesized using appropriate route and structures of compounds were determined by FT-IR, 1H NMR and Mass spectroscopy analysis. The synthesized compounds were evaluated for their invitro antibacterial potential using bacterial strain Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli where some of the compounds showed their activeness against the strain.

Authors and Affiliations

J. P. Jadhav, J. B. Mahyavanshi, M. B. Shukla, K. A. Parmar

Keywords

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  • EP ID EP626043
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How To Cite

J. P. Jadhav, J. B. Mahyavanshi, M. B. Shukla, K. A. Parmar (2018). Synthesis, Structure Elucidation and Biological Studies of 2-{[5-(4-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-arylacetamide derivatives. Journal of Biological and chemical Chronicles, 4(1), 42-47. https://www.europub.co.uk/articles/-A-626043