Target-Mediated Disposition Model Describing the Dynamics of IL12 and IFNγ after Administration of a Mifepristone-Inducible Adenoviral Vector for IL-12 Expression in Mice
Journal Title: The AAPS Journal - Year 2013, Vol 15, Issue 1
Abstract
The online version of this article (doi:10.1208/s12248-012-9423-9) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Zinnia Patricia Parra-Guillen, Alvaro Janda, Pilar Alzuguren, Pedro Berraondo, Ruben Hernandez-Alcoceba, Iñaki F. Troconiz
Engineered Mannitol Ternary Additives Improve Dispersion of Lactose–Salbutamol Sulphate Dry Powder Inhalations
The online version of this article (doi:10.1208/s12248-013-9476-4) contains supplementary material, which is available to authorized users.
Sequential Bioequivalence Trial Designs with Increased Power and Controlled Type I Error Rates
The online version of this article (doi:10.1208/s12248-013-9475-5) contains supplementary material, which is available to authorized users.
Current methodology to assess bioequivalence of levothyroxine sodium products is inadequate
Levothyroxine sodium is a drug with a narrow therapeutic index for which an individual patient must have his or her dose carefully titrated to achieve the necessary therapeutic effect. In addition, exogenous levothyroxin...
MicroRNA Regulation of Cancer Stem Cells and Therapeutic Implications
MicroRNAs (miRNAs) are a class of endogenous non-protein-coding RNAs that function as important regulatory molecules by negatively regulating gene and protein expression via the RNA interference (RNAi) machinery. MiRNAs...
Influence of the Molecular Weight of Bioreducible Oligoethylenimine Conjugates on the Polyplex Transfection Properties
The purpose of the present study was to investigate the influence of molecular weights on the chemical, biophysical, and biological properties of bioreducible oligoethylenimine conjugates. The cationic conjugates were sy...