Targeted Delivery of Curcumin to Tumors via PEG-Derivatized FTS-Based Micellar System
Journal Title: The AAPS Journal - Year 2014, Vol 16, Issue 3
Abstract
The online version of this article (doi:10.1208/s12248-014-9595-6) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Yichao Chen, Xiaolan Zhang, Jianqin Lu, Yixian Huang, Jiang Li, Song Li
Mass Spectrometry-Based Targeted Proteomics as a Tool to Elucidate the Expression and Function of Intestinal Drug Transporters
Intestinal transporter proteins affect the oral bioavailability of many drugs in a significant manner. In order to estimate or predict their impact on oral drug absorption, data on their intestinal expression levels are...
Performance Comparison of Various Maximum Likelihood Nonlinear Mixed-Effects Estimation Methods for Dose–Response Models
The online version of this article (doi:10.1208/s12248-012-9349-2) contains supplementary material, which is available to authorized users.
Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney
In the kidney, human organic cation transporters (OCTs) and multidrug and toxin extrusion proteins (MATEs) are the major transporters for the secretion of cationic drugs into the urine. In the human kidney, OCT2 mediates...
Development of an In Vivo Ovine Dry Powder Inhalation Model for the Evaluation of Conventional and Controlled Release Microparticles
Microparticles of DSCG alone or with 90% w/w PVA where prepared and characterised as described previously (5,6). Briefly, DSCG was spray dried under optimised conditions to produce a yield of microparticles with desired...
Challenges in Development of Nanoparticle-Based Therapeutics
In recent years, nanotechnology has been increasingly applied to the area of drug development. Nanoparticle-based therapeutics can confer the ability to overcome biological barriers, effectively deliver hydrophobic drugs...