Targeting Calcitonin Gene-Related Peptide and its Receptor by Monoclonal Antibody, New Developments in the Prevention of Migraine
Journal Title: Neuro – Open Journal - Year 2015, Vol 2, Issue 3
Abstract
Migraine is a chronic headache disorder with an unknown pathophysiology. Research in the past decade has shown that to be a brain disorder, a dismodulation of sensory processing affecting vascular tone and pain1-3 but since the exact pathomechanism of migraine is not very well known, its treatment is also difficult. Current drugs recommended by the “European Federation of Neurological Societies (EFNS)” used in the treatment of migraine include the triptan family drugs that are serotonin (5-HT1B/D) receptor agonists, and the Non-Steroid Anti-Inflammatory Drugs (NSAIDs).4 Several other drugs such as anti-epileptic drugs, beta-blockers, and calcium channel blockers are also recommended in the treatment of migraine.4
Authors and Affiliations
Mohtashem Samsam
Keywords
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- EP ID EP552601
- DOI 10.17140/NOJ-2-e004
- Views 151
- Downloads 0
Targeting Calcitonin Gene-Related Peptide and its Receptor by Monoclonal Antibody, New Developments in the Prevention of Migraine
Migraine is a chronic headache disorder with an unknown pathophysiology. Research in the past decade has shown that to be a brain disorder, a dismodulation of sensory processing affecting vascular tone and pain1-3 but si...
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