Targeting Calcitonin Gene-Related Peptide and its Receptor by Monoclonal Antibody, New Developments in the Prevention of Migraine
Journal Title: Neuro – Open Journal - Year 2015, Vol 2, Issue 3
Abstract
Migraine is a chronic headache disorder with an unknown pathophysiology. Research in the past decade has shown that to be a brain disorder, a dismodulation of sensory processing affecting vascular tone and pain1-3 but since the exact pathomechanism of migraine is not very well known, its treatment is also difficult. Current drugs recommended by the “European Federation of Neurological Societies (EFNS)” used in the treatment of migraine include the triptan family drugs that are serotonin (5-HT1B/D) receptor agonists, and the Non-Steroid Anti-Inflammatory Drugs (NSAIDs).4 Several other drugs such as anti-epileptic drugs, beta-blockers, and calcium channel blockers are also recommended in the treatment of migraine.4
Authors and Affiliations
Mohtashem Samsam
Targeting Calcitonin Gene-Related Peptide and its Receptor by Monoclonal Antibody, New Developments in the Prevention of Migraine
Migraine is a chronic headache disorder with an unknown pathophysiology. Research in the past decade has shown that to be a brain disorder, a dismodulation of sensory processing affecting vascular tone and pain1-3 but si...
Radiation Therapy and Nimotuzumab in Children and Adolescents with Brainstem Gliomas: A 5-Year Institutional Experience
Background: Brainstem gliomas (BSG) are Central Nervous System (CNS) tumors with a median survival time of approximately 9 months. Up to now chemotherapy has not shown to improve survival in these patients. The outcome o...
The Diagnostic Role of Neuromuscular Ultrasound in Chronic Inflammatory Demyelinating Polyneuropathy
The immune-neuropathies are a heterogenous group of peripheral nerve disorders. Their diagnostic classification is mainly based on the documentation of the distribution pattern of peripheral nerve impairment and the resu...
Neurovascular Conflicts of Cerebellopontine Angle: A Review of the Literature
The pathology of the cistern of the cerebellopontine angle is primarily the disease of the nervous and vascular structures that it contains and of the meninges that line it. It appears by the Trigeminal Neuralgia (TN), H...
Brain Gray Matter Changes Associated with Mindfulness Meditation in Older Adults: An Exploratory Pilot Study using Voxelbased Morphometry
Background: Mindfulness-based interventions (MBIs) have previously been associated with structural gray matter changes in normal healthy adults. However, it remains unknown if standardized MBIs can induce similar changes...