The Applications of Human Umbilical Cord Mesenchymal Stem Cells to Treat Spinal Cord Injuries
Journal Title: Journal of Regenerative Medicine & Biology Research - Year 2023, Vol 4, Issue 2
Abstract
Due to the morbidity and resulting lifestyle changes of Spinal Cord Injuries (SCI), there has been an extensive need to evaluate potential treatments. Mesenchymal cells hold the capacity to address both the primary and secondary mechanisms of SCI. Human Umbilical Cord stem cells (hUC), in particular, show promise due to their rapid proliferation, immunological properties, and pluripotent capacity. These hUC-MSC can be isolated from the umbilical Cord Blood (hCB) and Wharton’s jelly, a viscous gel that maintains the umbilical cord’s integrity. While Wharton’s jelly-derived hUC-MSCs appear to have a greater capability for the treatment of SCI due to their increased proliferation, hCB-MSC additionally has long-term therapeutic potential in clinical trials.
Authors and Affiliations
Erin Jones, Vincent S Gallicchio
Keywords
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- EP ID EP716898
- DOI https://doi.org/10.46889/JRMBR.2023.4205
- Views 49
- Downloads 0
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