The Association of Serum Mg Levels with Stroke and Its Comparison with Control Group
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 3
Abstract
Abstract: Stroke is a major health issue & cause of death also, leaving patients with serious disabilities & mental stress. The incidence of stroke is highest among diabetics and people with hypertension. Research is going on to find out the other risk factors which may be associated with stroke risk. Risk of stroke is associated with many minerals, as showed by the recent studies. Normal levels of the mineral could decrease the risk; Magnesium has beneficial effects on blood pressure and on diabetics [2]. It was reported by researchers at Stocklom's Karolinska Institute that for every 100 milligram increase in magnesium intake, the risk of developing type 2 diabetes is decreased & have beneficial effect on hypertension also. Find out the association of Serum Mg levels with Stroke and its comparison with control group. Find out the association of Serum Mg levels with Stroke and its comparison with control group. The present study was conducted in 150 control and 150 cases that were admitted & came for follow up under Internal Medicine & Super Specialty department (Neurology) OPD during interval of 1 year from March 2016 to August 2017. Out of 150 cases, 90 were Ischemic, 45 were hemorrhagic and 15 were TIA. 0ut of 150 cases, 85 were male and 65 were female [m>f]. Number cases were in the age group of 40-80 years. In our study, the serum magnesium level is lower in stroke patients who had stroke as compare to control group who did not have as compare to normal in case group. Hypomagnesaemia patients are prone to develop diabetes. Deficiency of magnesium is associated with in atherogenic alteration in blood lipid & hence more prone to Thrombotic/Haemorrhagic & TIA. The significant conclusion of this study is that low serum magnesium level is associated with acute neurological complication like ischemic or hemorrhagic stroke & if supplemented can prevent stoke of all types by 15%. Normal value 1.70 to 2.2 mg/dl or 0.85 to 1.10 mmol/L. Serum Mg level in stroke patients is ischemic stroke were (mean) 1.45 ± 0.41 hemorrhagic stroke group was 1.24 ± 0.32 & highest being in TIA followed Ischemic group & minimum in hemorrhagic group. Pair wise comparison to ischemic to hemorrhagic / TIA to hemorrhagic, TIA to Ischemic as shown in table but was non-significant in Ischemic to hemorrhagic but highly significant in TIA to hemorrhagic, & TIA Ischemic
Authors and Affiliations
Dr. Bushra Khanam, Dr. Prashant Joshi, Dr. Nelson Ghosh, Dr. Praveen Kavuri
Keywords
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