The comparison of total antioxidant capacity of serum and saliva between patients with type-2 diabetes mellitus and control
Journal Title: مجله دانشگاه علوم پزشکی شهرکرد - Year 2005, Vol 7, Issue 3
Abstract
Background and aim: In human body, there are a number of special systems to defend the damages caused by antioxidant. In some diseases the defense system against antioxidant activity alters and this alteration may be used in recognizing and the processing of different diseases. Diabetes is one of the most common and important chronic illnesses in which the antioxidant capacity is altered. The aim of this research was to determine and compare the antioxidant capacity of both serum and saliva of diabetics compare to the control group. Method: This is a cross - sectional research in which those under studying are 42 people of with typeII diabetes mellitus coming and going to the Arak diabetes center as the case group with 42 people of control group which were in the same age and sex with the people in the case group from the point of total antioxidant capacity in serum and saliva were compared. The capacity of antioxidant in serum and saliva was measured by FRAP method. Results: The average and standard deviation (mean±SD) of the total antioxidant capacity of serum and saliva in case group were in range: 2.51±0.088, 1.90±0.110 and in control group were: 2.90±0.107, 1.97±0.098 . (P=0.001, 0.74) From the statistical viewpoint, the increase in the total antioxidant capacity of serum in case group was meaningful, but the decrease in the total antioxidant capacity in saliva was not meaningful. Conclusion: Our results showed that the antioxidant capacity in the patients, s serum was higher than that in the control group. However, this difference was not observed in the saliva of these two groups. Conclusively, if this capacity of antioxidant is used in recognizing and processing of the disease, this difference should be taken into account.
Authors and Affiliations
Aliakbar Malekirad, Saidmohamad Ali Shariatzadeh , Ali Fani, Akram Ranjbar
Keywords
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