The correlation between cerebral perfusion and auditory cognitive ability in patients with amnestic mild cognitive impairment
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 5
Abstract
[Objective] To explore the correlation between changes in cerebral blood flow and auditory cognitive function in patients with amnestic mild cognitive impairment (aMCI). [Methods] The aMCI patients who visited the Memory Clinic of Beijing Friendship Hospital from July 2022 to September 2023 were selected as the research subjects, and gender and age matched healthy controls were included in the comparative study. All subjects underwent ASL scans using 3.0 T MRI and underwent a Chinese "repeat-recall" verbal cognitive function test (RRT) as an assessment of auditory cognitive abilities, and the correlation between cerebral blood flow (CBF) changes and auditory cognitive function was finally analyzed. [Results] A total of 26 patients with aMCI and 32 normal healthy were included. Regardless of the high and low context and signal to noise ratio (SNR), the auditory cognitive ability of the aMCI group significantly decreased compared to the control group (P<0.01). The standardized CBF value of the left inferior parietal lobule in the aMCI group was significantly reduced compared to the control group (0.921±0.234 vs 1.247±0.076, P<0.001). Correlation analysis showed that the standardized CBF value of the left inferior parietal lobule in the aMCI group was correlated with auditory cognitive ability under low contextual conditions of -5 dB signal-to-noise ratio (r=0.857, P<0.001). [Conclusion] CBF in the left inferior parietal lobe in patients with aMCI may have some relevance for auditory cognitive impairment.
Authors and Affiliations
Haitao LI, Jiayuan SHEN, Huiqin YAN, Xiaoshuai LI, Yuhe. LIU
Keywords
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- EP ID EP750504
- DOI 10.3969/j.issn.1002-0152.2024.05.005
- Views 78
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