The effect of Licophar on prevention of oral mucositis caused by chemotherapy in cancer patients
Journal Title: مجله علمي دانشگاه علوم پزشكي كردستان - Year 2017, Vol 22, Issue 90
Abstract
Background and Aim: Oral mucositis is a common and debilitating complication that can occur after administration of certain chemotherapy drugs. Yet, no preventive therapy has been recommended for this complication. This study aimed to determine the effect of licophar on prevention of chemotherapy-induced oral mucositis. Methods and method: This was a double blind RCT which was performed in Sanandaj City and included 40 patients with colon and gastric cancer who had received chemotherapy for the first time between 1390 and 1391. 5-FU (FOLFOX4) was prescribed for the patients. Licophar was given to the intervention group, and control group received placebo. The patients were examined for the presence or absence of oral mucositis. Using SPSS.18 software, data were analyzed by descriptive statistics and Mann-Whitney tests, independent T test and chi square. Results: In our study, 25 patients (62.5%) were male and 15 (37.5%) were female. The mean age of the participants was 53.20 ±8.77 years and the mean duration of treatment was 5.05 ±3.15 months. Oral mucositis was not observed in the intervention group, but 35% of the patients in the control group developed this disorder (p <0.01). There were no statistically significant difference between the two groups in relation to age and gender (p> 0.05). Conclusion: Licophar is effective for prevention of oral mucositis induced by chemotherapy.
Authors and Affiliations
MD B Ghaderi, MD Sh Aghayani, MSc N Daneshkhah, MD N Moghimi
Keywords
Related Articles
- EP ID EP282918
- DOI -
- Views 128
- Downloads 0
Evaluation of antibacterial properties of alcohol and water extracts of propolis on Bacillus pumilus, Pseudomonas syringae and Serratia plymuthica
Background and Aim: Propolis is one of the most important bee products which has antibacterial property. This study was conducted to investigate antibacterial activity of propolis on Bacillus pumilus, Pseudomonas syringa...
Effect of prenatal immobilization stress on spatial memory, anxiety-like behavior and brain BDNF concentration in the F1 generation male mice
Background and Aim: In this study, we investigated the effect of immobilization stress during pregnancy on the spatial memory, anxiety-like behavior and brain BDNF level in F1 generation male NMRI mice. Materials and Met...
Intensity of depression, its predictive and mediating factors in the patients with chronic headache
Background and Aim: Headache is often associated with depression. However, depressive symptoms are more severe in some patients. The aim of the present study was to compare different types of chronic headache in regard t...
Comparison of two protocols for induction of differentiation of human adipose derived stem cells into oligodendrocyte progenitor cells
Background and Aim: Multiple sclerosis (MS) is an autoimmune demyelinating disease which affects central nervous system (CNS). The aim of this study was to provide a simple, short term and efficient method for differenti...
Effect of cardiac rehabilitation on physical and mental health components: a randomized controlled clinical trial
Background and Aim: Cardiovascular disease can affect physical and mental conditions. The purpose of the present study was to investigate the effect of phase 1 and 2 of cardiac rehabilitation on physical and mental healt...