The effect of neuromodulation and continuous brachial plexus block for treatment of critical upper limb ischemia in the course of septic shock: a case report

Journal Title: BÓL - Year 2015, Vol 16, Issue 2

Abstract

Sepsis is a set of clinical symptoms and pathophysiological signs described as generalized inflammatory response provoked by infection. Septic shock is an effect of hypovolemia caused by inflammatory mediators. They provoke an increase of vascular wall permeability and wield negative inotropic effects followed by hypotension and tissue hypoperfusion. Around the globe, sepsis remains the third most frequent cause of mortality within the infectious diseases group and tenth among the general population (50-100/100 thousand people/year). 16% of patients hospitalized in Intensive Care Units in Poland is diagnosed with severe sepsis and mortality rate approximates 54%. High incidence of sepsis in Intensive Care Units poses a serious health threat with severe medical and socioeconomic consequences considering the signifiant mortality rate, long treatment periods and their cost. Circulatory centralization providing oxygenation of vitally important organs poses a threat of inadequate blood supply to peripheral and superfiial tissues which may lead to necrosis. Female 40 year-old patient was diagnosed with severe septicshock in course of peritonitis caused by perforation of gastro-intestinal duct. Course of septic shock and action of vasoconsticting medications led to critical ischemia of distal parts of upper and lower limbs. Due to lack of capacity for systemic treatment of ischemia, neuromodulation followed by continuous block of both brachial plexuses was employed. Peripheral vasodilatation obtained by plexus continuous neuromodulation and block provided increased distal tissue perfusion in both hands. There was no signifiant antagonism to vasoconstrictive action of catecholamines. Neuromodulation of brachial plexuses and continuous block decreased long term negative effects of treatment facilitating aversion of amputation of both hands which would inevitably decrease patient’s quality of life.

Authors and Affiliations

Patrycja Mirończuk, Wojciech Nierodziński, Katarzyna Kapica, Piotr Lisowski

Keywords

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  • EP ID EP76541
  • DOI 10.5604/1640324x.1164806
  • Views 109
  • Downloads 0

How To Cite

Patrycja Mirończuk, Wojciech Nierodziński, Katarzyna Kapica, Piotr Lisowski (2015). The effect of neuromodulation and continuous brachial plexus block for treatment of critical upper limb ischemia in the course of septic shock: a case report. BÓL, 16(2), 27-34. https://www.europub.co.uk/articles/-A-76541