The Effect of Omega-3 Supplementation on Serum Inflammatory Factors in Hemodialysis Patients
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 20, Issue 7
Abstract
Background: The level of inflammatory factors such as tumor necrosis factor-alfa (TNF-α) and C-reactive protein (CRP) is increased in ESRD patients and is associated with incremental mortality in these patients. Omega-3 is known as a regulator of inflammatory system. The aim of this study is to evaluate the effect of omega-3 supplementation on TNF-α and CRP level in ESRD patients. Methods: In this randomized _ controlled double-blind clinical trial, 54 ESRD patients were evaluated in two hemodialysis centers of Isfahan university hospitals. TNF-α and high specific-CRP (hs-CRP) were measured. In the experimental group, Patients were treated with Omega-3 capsules (1 gram capsules- Making factory Zahravi- containing Eicosapentanoic 180 mg and Dosahexanoic 120 mg) three capsules per day (3 g/day ) and the control group received placebo capsules manufactured by the Zahravi with the same shape and size for 6 consecutive months. Results: There were no differences in CRP and TNF-α levels in the beginning and the end of study between two groups (P > 0.05). Conclusion: We conclude that using 3 g of omega-3 per day for 6 consecutive months caused no significant effect on serum levels of TNF-α and CRP in the heamodialysis population .Further studies with larger numbers of patients and longer duration of treatment are recommended.
Authors and Affiliations
Yaser Salehi, Firouzeh Moinzadeh, Mojgan Mortazavi, Mohsen Hoseini, Shahaboddin Dolatkhah, Shahram Taheri, Amirhosein Salehi
Keywords
Related Articles
- EP ID EP311443
- DOI 10.9734/BJMMR/2017/27659
- Views 87
- Downloads 0
The Renal Ultrasound in Patients with Acute Kidney Injury
Aims: Acute Kidney Injury (AKI) is seen in 15% of hospitalized patients and a renal ultrasound (RUS) is often ordered to exclude an obstructive cause in the initial evaluation of AKI. This study was done to evaluate the...
Perception of Self-esteem and Body Image among Women with Breast Cancer of a University Hospital in Tunisia
Background: Breast cancer is a major public health problem. It represents the first female cancer which creates physical, psychological and social disorders. Objectives: This study aimed to describe the perception of the...
Unexpected and Disruptive Changes in Admissions Associated with an Infectious-like Event Experienced at a Hospital in Berkshire, England around May of 2012
Aims: To study the effect of a large infectious-like event on admissions to, and bed occupancy in, a very large acute hospital in Reading (western Berkshire) England, observed to commence in the early part of 2012. These...
Temporal Bone Squamous Cell Carcinoma the Outcome of Radical Surgery as an Initial Treatment
Aims: The aim of this study is to analyse the clinical data and management of patients with temporal bone carcinoma and to discuss the management outcomes. Study Design: Retrospective study Place and Duration of Study:...
Evaluation of the Knowledge, Attitude and Practice of the Use of Insecticide- Treated Nets (ITNs) in Aba, Nigeria
Background: Over the past decade, significant gains have been made in the implementation of malaria preventive measures in sub-Saharan Africa, including the distribution of insecticide treated nets (ITNs). These have bee...