The effect of salvia officinalis tablet on hot flashes, night sweating, and estradiol hormone in postmenopausal women
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 8
Abstract
Hot flashes and night sweats associated with menopause are the most annoying symptoms among premenopausal women and have been ranked as the first reason for referral to medical centers. The common treatment for this symptom is administration of Hormone Replacement Therapy (HRT) that has some adverse effects and is sometimes contraindicated. Therefore, use of herbal drugs that have fewer side effects needs to be investigated. This study aimed to investigate the influence of salvia tablets on hot flashes, night sweats, and estradiol hormone in postmenopausal women referring to healthcare centers in Shiraz. This double-blind randomized clinical trial was performed on 100 qualified postmenopausal women with hot flashes. The study women were divided into two groups daily treated with 3 salvia or placebo tablets (100 mg) for 8 weeks. Estradiol hormone and menopause symptoms were evaluated using Menopause Rating Scale(MRS)1 week before and 8 weeks after the beginning the intervention. Besides, duration, intensity, and frequency of hot flashes and night sweats were evaluated every week, and the two groups were compared in terms of these variables. The results showed no significant difference between the two groups regarding demographic information, hot flashes, night sweats, and other menopause symptoms in MRS scale before the intervention. After 8 weeks, however, hot flashes, night sweats, and MRS scores significantly decreased in the saliva group compared to the control group. However, no significant difference was observed between the two groups concerning the estradiol levels. Yet, the results of intra-group analysis showed that the level of this hormone increased in the sage group. Sage tablets were effective in treatment of hot flashes, night sweats, and other menopausal symptoms in postmenopausal women. Thus, they can be considered as an alternative therapy for the individuals who are not able to use HRT.
Authors and Affiliations
SimaKiani rad| Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran, Sedighe Forouhari| Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Corresponding E-mail: forouharism@yahoo.com, Alamtaj Samsami Dehaghani| Infertility Research Center, Reproductive Endocrinology and Infertility Division, Department of OBGYN, School of Medicine Shiraz University of Medical Sciences, Shiraz, Iran, HomeiraVafaei| Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran, Mehrab sayadi| Student of biostatistics, Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran, Maryam Asadi| Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
Keywords
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