The Evaluation of the Relation Between Drug Compliance and Psychometric Tests in Chronic B Hepatitis Patients Who are Treated with Oral Antivirals
Journal Title: Viral Hepatitis Journal - Year 2019, Vol 25, Issue 3
Abstract
Objectives: Hepatitis B is a viral infection that causes acute and chronic hepatitis and serious complications such as cirrhosis and hepatocellular cancer. Several psychiatric symptoms and depression, particularly anxiety, can be seen in patients. Evaluation of the relation between medication adherence and psychometric tests in patients with Chronic hepatitis B (CHB) who are treated with oral antivirals is aimed in this study. Materials and Methods: Two hundred and fifty-nine patients were included in this study. Sociodemographic data form, Morisky 8 scale, Beck Anxiety scale (BAS) and Beck Depression scale (BDS) have been applied to the patients. Results: The age of the patients vary from 17 to 80, average age of the patients is foud as 46.04. A hundred eleven of the patients were women (42.9%). Two hundred and seven patients had no sign of depression (79.9%) and 52 of the patients (20.1%) had depression. The drug compliance was low in patients whose BDS scores were decreased. It has been found out that 195 of the patients had lowgrade of anxiety (75.3%), 26 of the patients had midgrade of anxiety (10%), and 38 of the patients had high-grade of anxiety (14.7%). The medication adherence was low in patients whose BAS scores were decreased. Conclusion: Anxiety and depression are frequent in CHB patients. Therefore, CHB patients should be followed up psychiatrically and should be addressed to the psychiatry specialist when necessary. Depression and anxiety influences the drug compliance. Further studies are required for evaluation the relation between the medication adherence and the level of anxiety and depression in CHB patients.
Authors and Affiliations
Esma Kepenek, Kurt Bahar Kandemir
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http://viralhepatitisjournal.org/archives/archive-detail/article-preview/the-effect-of-switch-treatment-on-liver-fibrosis-a/40275
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