THE FREQUENCY OF ABO BLOOD GROUPING AND RHESUS ANTIGENS AMONG SUDANESE BLOOD DONORS
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 4
Abstract
Back Ground: ABO and Rhesus (Rh) blood group antigens are hereditary characters and are useful in population genetic studies, resolving medico-legal issues and more importantly in pre-transfusion testing in blood banking practice. Relatively little information is available regarding the frequency of the ABO and various Rhesus antigens among Sudanese population. The study was aimed to determine the frequency of those antigens among the Sudanese blood donors. Material and Methods The Study was descriptive cross sectional study, performed during May and July 2013. A total of 385 male blood donors attending Al-amal Hospital from different Sudanese ethnic groups was included in this study. The blood samples collected into EDTA containers and tested for the ABO and Rhesus typing by classical slide and tube agglutination method using commercially available anti-sera and gel micro typing system. Data were analyzed using SPSS software computer program version 21. Result: Blood group (O) was the most predominant blood group (47%), followed by blood group A (30.9%), B (17.9%) and AB (4.2%). Majority of the subjects were Rh (D) positive (93.5%) and only (6.5%) were Rh negative. The predominant Rh antigen after Rh D was Rh e- ( 93.2%) followed by c- (81.6% ) , C (38.4% ) and E (16.9%). the most common phenotype in Rh D positive samples was ccDee(42.1%) and in RhD negative it was ccdee (5.2%) .Seven samples were negative for antithetical antigens E and e while five samples negative for C and c antigens. The most probable genotype was cDe/cDe (42.1%). Conclusion concluded that the frequency of the Rh antigens can be shown in this order D > e- > c- > C > E. Special precautions need to be undertaken to minimize any possible allo-immunization by such antigens.
Authors and Affiliations
Dr. Abdel Rahim Mahmoud Muddathir
Keywords
Related Articles
- EP ID EP628268
- DOI -
- Views 197
- Downloads 0
IN VITRO STUDY SHOWING THE ACTIVITY OF MATRIX METALLOPROTEINASE-2(MMP-2) ON GELATIN AND THE EFFECT OF CHELATING AGENT (1, 10 PHENANTHROLINE) ON THE REACTION
The Matrix Metalloproteinase-2 (MMP-2) is a zn2+ dependent enzyme that plays a crucial role in degradation and remodelling of extracellular matrix. Matrix metalloproteinase-2 is expressed in gliomas and other causing cel...
YOGA DARSHANA AND AYURVEDA-A BIRD’S EYE VIEW
Yoga Darshana and Ayurveda are integral part of each other and harmonize each other. The concepts of Yoga Darshana are selectively integrated in Ayurveda to suit its objectives viz., ‘Swasthya Rakshana‟ (maintaining the...
DESIGN, FORMULATION, AND EVALUATION OF CARBOPOL 940 AND XANTHAN GUM AS GEL BASES FOR ORAL LOCAL DRUG DELIVERY FOR ORAL MUCOSAL INFECTIOUS DISEASES
Local drug delivery systems have been used for a long time; in particular, for the local therapy of diseases affecting the oral cavity. Oral mucosa diseases are among the most common diseases affecting humans, and they c...
ANAESTHETIC TECHNIQUES IN DAY CASE UROLOGICAL SURGERIES IN BENUE STATE UNIVERSITY TEACHING HOSPITAL (BSUTH), MAKURDI, NIGERIA.
Background: The global economic constraints and increasing financial awareness has led to an increase in day case surgeries because there is reduction in healthcare cost. Day case surgery also gives rise to reduction of...
ACHIEVING AND PROMOTING HEALTHY LIFESTYLE BY SELF-MONITORING HABIT
India is battling a full-blown health crisis. Lancet study should be treated as a warning to our policymakers. Research reveals a dangerously rapid epidemiological transition and a rising burden of non-communicable disea...