The histopathological effects of salvia officinalis on the kidney and liver of rats
Journal Title: Scientific Journal of Medical Science - Year 2013, Vol 2, Issue 3
Abstract
The aim of this investigationwas to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old)were randomly assigned into two groups; A and B. Aqueous extract of S.officinalis leaves (300 mg/kg body weight) was administered orally to therats in group B while the rats in group A received equal volume of normalsaline for 14d. At termination of treatment, the histopathology of the kidneyand liver were assessed. The kidney and the liver in the extract treated ratdisplayed organized and preserved histological profile. Our findings suggestthat S. officinalis has no deleterious effects on the kidney and liverof the rats.
Authors and Affiliations
D. A. Adekomi*| Department of Anatomy and Cell Biology, Obafemi Awolowo University, Ile-Ife, Osun State, Nigeria., T. D. Adeniyi| Department of Anatomy, College of Medicine, Osun State University, Osogbo, Osun State, Nigeria., A. M. Afodun| Department of Anatomy, Faculty of Basic Medical Sciences, University of Ilorin, Ilorin, Nigeria., K. K. Quadri| Department of Physiology, University of Lagos, Lagos, Nigeria.
Keywords
Related Articles
- EP ID EP1225
- DOI -
- Views 835
- Downloads 36
Malignant melanoma of the nasal septum "a rare case"
The nose is an uncommon site for a malignant melanoma, representing 2% to 5% of head and neck malignant melanoma. Nasal malignant melanoma develops from the melanocytes residing in mucous membranes that have migrated dur...
Treatment of obesity: medical managements
Obesity is a very complex illness. It is one of the most prevalent diseases in the western world, its importance lies in the comorbidities that surround it, as well as the predisposition to cardiovascular events and othe...
Carotid artery intima-media thickness is a marker for coronary artery disease
Although cardiac mortality has declined over the past four decades, coronary artery disease (CAD) remains the leading cause of mortality worldwide. Considering the importance of CAD and effectiveness of primary preventi...
Development potential of pharmaceutical industry in transition countres
Contemporary medicine is striving to bring man closer to the ideal of eternal life. This ideal is, of course, unattainable within the boundaries of currently existing knowledge, but the breakthroughs in extending lif...
The histopathological effects of salvia officinalis on the kidney and liver of rats
The aim of this investigationwas to evaluate some of the effects of aqueous leaf extract of Salvia officinalis on the kidney and liver of male Sprague Dawley rats. Ten Sprague-Dawley rats (7-11 weeks old)were randomly as...