The Importance of Clinical and Diagnostic Markers of Aggression of Non-Functional Pituitary Adenomas
Journal Title: Міжнародний ендокринологічний журнал - Year 2015, Vol 6, Issue 70
Abstract
Sixty patients with non-functional pituitary adenomas were observed. Most patients had large-cell chromophobe pituitary adenomas (81.6%). Small-cell chromophobe adenomas occurred in 10 % cases. Only 1 patient (3.3 %) had giant carcinoma with regrowth and metastasis into the brain. Markers of aggression of non-functional pituitary adenomas are the young age of a patient, expressed first symptoms of disease manifestation, large size of tumor, asymmetry and deformation of pituitary, invasion of tumor to the neighboring tissues/arteries/cavernous sinus, presence of small cell and dark-cell chromophobe adenoma, panhypopituitarism.
Authors and Affiliations
Yu. M. Urmanova, Z. Yu. Khalimova, R. B. Faizullaev, M. Yu. Shakirova, D. Sh. Kholova
Keywords
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