The Incidence of Prostate Adenocarcinoma in Patients Who Underwent Cystoprostatectomy for Invasive Baldder Cancer and Histopathological Examination
Journal Title: Üroonkoloji Bülteni - Year 2016, Vol 15, Issue 2
Abstract
Objective: It was aimed to evaluate the incidence of prostate adenocarcinoma in patients treated by cystoprostatectomy for invasive bladder urothelial carcinoma and to demonstrate the histopathological features of prostate cancer cases. Materials and Methods: Between January 2010 and April 2015, totally 119 invasive bladder urothelial carcinoma patients operated by cystoprostatectomy without the diagnosis of prostate adenocarcinoma preoperatively were included into the study. The pathological records of patients were analyzed retrospectively. The patients were classified according to TNM system. Results: Prostate adenocarcinoma was detected in cystoprostatectomy materials of 16 patients (13.4%) and only 4 of the patients (25%) had clinically substantial prostate cancer. The average age was 62,3 (43-78, range) years. The pathological results of bladder urothelial carcinoma revealed as T2a in 4 (25%) patients, T2b in 4 (25%) patients, T3a in 6 (37.5%) patients and T4 only in 2 (12.5%) patients. Lymph node metastasis was detected in 5 (31.2%) patients and carcinoma in situ was detected in 5 (31.2%) patients. The mean follow-up time was 27.1 (463) months. The Gleason score of prostate cancer was 3+3 in 12 (75%) patients, 3+4 in 2 (12.5%) patient, 4+4 in 1 (6.25%) patient and 4+5 in 1 (6.25%) patient. The stages of prostate cancer were T2a in 14 (87.5%) patients, T2b in 1 (6.25%) patient and T3a in 1 (6.25%) patient. Conclusion: Life expectancy of the patients who had radical cystoprostatectomy due to invasive bladder tumor was affected dramatically by the pathological stage of urothelial carcinoma. Therefore, prostate-sparing radical cystectomy techniques can be used as alternative surgical methods for younger and chosen patients to minimize continence and erectile problems and to improve the quality of life.
Authors and Affiliations
Yasin Ceylan, Volkan Şen, Salih Polat, Bülent Günlüsoy, Tansu Değirmenci, Yusuf Kadir Topçu, Deniz Bolat, Zafer Kozacıoğlu
Keywords
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- EP ID EP228336
- DOI 10.4274/uob.647
- Views 109
- Downloads 0
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