The management of diffuse large B-cell lymphoma
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2010, Vol 27, Issue 1
Abstract
Diffuse large B-cell lymphoma (DLBCL) is the most common histologic type among the lymphomas. It is an aggressive neoplasm but also constitutes a therapeutic challenge since in many cases it can be cured, due to its inherent chemosensitivity. The biology and the clinical course of DLBCL are highly heterogenous and efforts have been made to identify clinical risk factors in order to apply a stratification system. A plethora of chemotherapeutic combinations have been used to treat DLBCL, but the CHOP regimen remains the treatment of choice for the majority of patients. The addition of rituximab to CHOP (immunochemotherapy) represents a significant step forward, and this has been widely accepted as the standard combination. Many questions, however, are still unanswered, and for many patients the outcome of treatment falls short of expectations. This paper provides a comprehensive review of the prognosis of primary nodal DLBCL and its first-line treatment.
Authors and Affiliations
K. LIAPIS, T. KARMIRIS
Keywords
Related Articles
- EP ID EP83460
- DOI -
- Views 99
- Downloads 0
The renal microcirculation and biomarkers in acute kidney injury of ICU patients
Αcute kidney injury is related with a high mortality rate in hospitalized and critically ill patients. The need for immediate recognition and management of acute kidney injury highlights the importance of the underlying...
Pill esophagitis induced by tetracycloin treatment
No abstract available
Philosophers' answer: Four possible answers: when time has come; no wish to live anymore; not worth living; body cannot sustain life
What does the question "when should a person die?" actually mean? How the verb 'should' ought to be understood in this context? In this presentation I start by focusing on the term 'should'. I argue that the verb 'should...
Solitary bone cyst
No abstract available
Ιnter-university harmonization for the development of subspecialties of consultation-liaison:<br /> Psychiatry, old age psychiatry and forensic psychiatry. Consensus statement of the Hellenic College of Academic Psychiatry <br /> <br />
Τhe voluminous amount of new knowledge and the strong academic standing of consultation-liaison psychiatry, old age and forensic psychiatry lead to their establishment as subspecialties of psychiatry in many countries. I...