The Master Code of Biology: Self-assembly of two identical Peptides beta A4 1-43 Amyloid In Alzheimer’s Diseases
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 4
Abstract
Fundamental research published enables us to unify, overall, the genomics and proteomics information of any genetic sequence. This fundamental law is based on a bio-mathematics unification of all genetic information (bio-atoms, nucleotides, codons, amino acids, DNA/RNA/ Proteins) from the level of the six basic bio-atoms C O N H S P to the global level of whole genomes. Concretely, the dynamics of this Genomics/ Proteomics Coupling is appeared as two correlated curves translating topology and the dynamic evolution of a hierarchical classification of codons throughout the studied sequence. More precisely, the study of these curves shows that this tool highlights the functional areas and active sites within proteins. The specific context of Proteins Self-Assembly area could be an interesting field to run and improve our new basic research approach. Particularly, studying Prions by this method we propose a possible Prion PRION self-interaction with a Genomics/ Proteomics correlation coupling ratio of r=99.3 Such prospects oblige us to propose this new theoretical biomathematics approach in the study of the Genetics of the disease of Alzheimer, particularly at the level of Amyloid Plaques
Authors and Affiliations
Jean Claude Perez
Keywords
Related Articles
- EP ID EP571638
- DOI 10.26717/BJSTR.2017.01.000394
- Views 140
- Downloads 0
Implementation of Rapid Response Flow Reduces the Waiting Time of Patients with Chest Pain in an Emergency Unit
Introduction: Chest pain (CP) is a frequent symptom in emergencies worldwide, presenting as a diagnostic challenge for the emergency room, due to the multiplicity of etiologies, and the diagnostic fluctuation between low...
Why is Tinnitus so annoying?
Animals have their hearing as a warning system for the first line of defence, which raises the alert. In humans, except from the basic innate “animal” reactions, we have our thoughts and feelings, with our sentiments and...
Juxtacortical Chondromyxoid Fibroma of Tibia
Introduction: Chondromyxoid fibroma, CMF, is the least common benign cartilaginous tumor composed of chondroid and myxoid matrix. It is usually located eccentrically in distal femur or proximal tibia metaphysis. Juxtacor...
Esophageal Choke and its Management in a Thorough Bred Horse
We describe the clinic case of a thoroughbred horse with esophageal obstruction that presented a fatal outcome, possibly attributed to inadequate management in which excessive use of the nasogastric tube to push the cont...
The Effect of Alcohol Intoxication on Mortality in Road Traffic Injury Patients at Level I Apex Trauma Centre in India
Alcohol consumption arising as leading risk factor for road traffic injuries and one of the major public health concerns globally. Alcoholism is associated with liver disease, coronary vascular disease, Hypertension, Str...