The prevention and treatment of peritoneal carcinomatosis from gastric cancer: A 2013 update
Journal Title: Journal of Cancer Research & Therapy - Year 2013, Vol 1, Issue 1
Abstract
Gastric cancer is the fourth most common cancer and the second leading cause of cancer death in the world. Penetration of the gastric serosa and lymphatic spread are the two most important factors affecting prognosis in gastric cancer. Patients with peritoneal carcinomatosis from gastric cancer show a particularly poor prognosis. A few treatment strategies have been tested and proposed to increase survival rates. The cornerstone of treatment remains complete cytoreductive surgery associated with a different combination of chemotherapy regimen. It has been demonstrated as systemic adjuvant, systemic neoadjuvant and above all hyperthermic intraperitoneal chemotherapy improve the survival, when used in the prevention and treatment of peritoneal carcinomatosis from gastric cancer. Few new molecules have been introduced enhancing the effect of chemotherapy by biologically targeting its objective. However further studies are needed.
Authors and Affiliations
Ansaloni L, Lotti M, Campanati L, Bertoli P, Poiasina E, Mandalà M, Coccolini F
Keywords
Related Articles
- EP ID EP550150
- DOI 10.14312/2052-4994.2013-8
- Views 80
- Downloads 0
Pharmacological and safety evaluation of CIGB-300, a casein kinase 2 inhibitor peptide, administered intralesionally to patients with cervical cancer stage IB2/II
CIGB-300 is a pro-apoptotic casein kinase 2 inhibitor peptide with potential anticancer action. An open-label and dose scaling Phase I trial was carried out to investigate the peptide tumor uptake, pharmacokinetics, toxi...
Calcification of peritoneum and peritoneal fluid perfusion malfunction in carcinomatosis of serous membranes of peritoneal cavity
The article describes the peritoneal calcification in peritoneal carcinomatosis, as well as its possible role in the development of carcinomatosis within the frames of the authors’ alternative theory. The analysis of the...
Multi-institutional analysis of bioimpedance spectroscopy in the early detection of breast cancer related lymphedema
Background: The purpose of this study was to evaluate bioelectrical impedance spectroscopy’s (BIS) ability to detect and monitor extracellular fluid accumulation of the upper limb as it relates to the extent of loco-regi...
Evaluation of tissue 5´-Nucleotidase as tumor marker in breast and brain tumors using receiver operating characteristic curve
The pursuit of the ideal tumor marker has generated many testes for using in the diagnosis and management of cancer. Several of which are now widely available. The objective of the current study was to evaluate 5´-NT act...
The prevention and treatment of peritoneal carcinomatosis from gastric cancer: A 2013 update
Gastric cancer is the fourth most common cancer and the second leading cause of cancer death in the world. Penetration of the gastric serosa and lymphatic spread are the two most important factors affecting prognosis in...