The probable interspecies transfer of the bla<sub>VIM-4</sub> gene between Enterobacter cloacae and Klebsiella pneumoniae in a single infant patient
Journal Title: Polish Journal of Microbiology - Year 2015, Vol 64, Issue 4
Abstract
We report interspecies transfer of the [i]bla[/i][sub]VIM-4[/sub] gene in MBL-producing [i]Enterobacter cloacae[/i] and Klebsiella pneumoniae isolates from a newborn patient who had received meropenem therapy. We show the evidence that bla[sub]VIM-4 [/sub]gene was transmitted as a part of the class 1 integron on a conjugative plasmid ca. ~90 kb. High homology of nucleotide sequence was observed between the integron found in VIM-4 producing [i]E. cloacae[/i] and [i]K. pneumoniae[/i] strains tested and class 1 integrons previously reported in [i]Pseudomonas aeruginosa [/i]from Hungary and Poland. This finding may suggest[i] P. aeruginosa[/i] as a potential source of the acquired VIM-4 in [i]Enterobacteriaceae[/i].
Authors and Affiliations
Katarzyna Piekarska, Magdalena Rzeczkowska, Tomasz Wołkowicz, Aleksandra Januszkiewicz, Edyta Podsiadły, Urszula Demkow, Rafał Gierczyński
Keywords
Related Articles
- EP ID EP81175
- DOI -
- Views 102
- Downloads 0
<strong>Comparison of Free and Immobilized L-asparaginase Synthesized by Gamma-Irradiated <em>Penicillium cyclopium</em></strong>
Gamma irradiation is used on [i]Penicillium cyclopium[/i] in order to obtain mutant cells of high L-asparaginase productivity. Using gamma irradiation dose of 4 KGy, [i]P. cyclopium[/i] cells yielded L-asparaginase with...
Application of Metagenomic Analyses in Dentistry as a Novel Strategy Enabling Complex Insight into Microbial Diversity of the Oral Cavity
The composition of the oral microbiome in healthy individuals is complex and dynamic, and depends on many factors, such as anatomical location in the oral cavity, diet, oral hygiene habits or host immune responses. It is...
Serotype-Specific Pneumococcal Status prior to PCV 13 Administration in Children and Adolescents with Inflammatory Bowel Disease
The aim of this study was to evaluate the serotype-specific pneumococcal status of children and adolescents with inflammatory bowel disease (IBD) who were naïve to pneumococcal vaccination before administering the 13-val...
<strong><em>Streptococcus anginosus</em> (<em>milleri</em>) group strains isolated in Poland 1996-2012 and their antibiotic resistance patterns</strong>
[i]Streptococcus anginosus[/i], [i]Streptococcus intermedius[/i] and [i]Streptococcus constellatus[/i] form group of related streptococcal species namely Streptococcus Anginosus Group (SAG). The group, previously called...
Morphological and Molecular Characterization of Phoma complanata, a New Causal Agent of Archangelica officinalis Hoffm. in Poland
The paper concerns the fungus Phoma complanata, isolated for the first time in Poland, from the roots and umbels of angelica (Archangelica officinalis) in 2009. The morphology of fungal isolates was tested on standard cu...