The state of the autonomic nervous system in patients with atopic dermatitis of adults

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The state of the autonomic nervous system in patients with atopic dermatitis of adults

Journal Title: ScienceRise: Medical Science - Year 2018, Vol 0, Issue 4

Abstract

Aim of the research: to establish the features of the vegetative nervous system (VNS) state in patients with atopic dermatitis (AD) of adults and its dependence on the severity of the course of dermatosis and the sex of patients, which will expand our knowledge of the pathogenesis of dermatosis in adults and develop additional methods of corrective therapy. Materials and methods. There were 117 patients under observation, including 80 patients with AD at the age of 18 to 45 years and 37 healthy persons. In the study of questionnaires by A.M. Wein in patients with AD, the dysfunction of the VNS was 29±4.2 points (in healthy individuals 8±2.2), which was more pronounced in women with AD in severe dermatitis. According to the parameters of heart rate variability in patients with AD, hypersympathicotonia predominated and humoral-metabolic influences on the regulation of heart rhythm. In patients with AD, a decrease in the reactivity and tone of the parasympathetic department of the VNS has been established. All these indicators were more representative in patients with severe dermatosis, especially in women. Result. Progression of the degree of severity of AD in adults, especially in women, leads to stress and exhaustion of regulatory and adaptive mechanisms of the VNS with an increase in the activity of its sympathetic link. This position of the cardiovascular system contributes to the preservation and progression of the skin process, and therefore is an unfavourable prognosis for recovery and requires additional corrective therapy. Conclusions. 1. It was found that the reactivity of the VNS has its own peculiarities in patients with AD, the dependence of the severity of its changes according to the data of the A.M. Wein questionnaire, the sex of the post-lingual, the features of the course and clinical manifestations, especially the severity of the skin process. 2. In the patients studied, hypersympathicotonia predominated and humoral-metabolic manifestations affected the regulation of the heart rhythm with reduced total power of the spectrum, a decrease in the tone of the parasympathetic section of the VNS, and an increase in the influence of humoral-metabolic mechanisms, especially in patients with more severe blood pressure

Authors and Affiliations

Yuliya Popovich

Keywords

atopic dermatitis. sex. heaviness. heart. rhythm. patients. allergies. autonomic nervous system

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EP ID EP646421
DOI 10.15587/2519-4798.2018.132698
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