The Study of Efficacy and Induction –Abortion Interval of Single Dose of Vaginal Misoprostol 800 µg In First Trimester Abortion.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2018, Vol 1, Issue 6
Abstract
Background: Medical abortion is a safe, effective means of terminating pregnancy provided the criteria are fulfilled. Hence acceptable in both the developing and developed countries of the world. The usage of pharmacological agents such as Mifepristone, Misoprostol or in combination in various regimens is adopted for MTP. Objectives: To know the efficacy and outcome of single dose of vaginal Misoprostol 800Ug in first trimester abortion. Material And Methods: This study was conducted over a period of 3 years at JLNMCH Bhagalpur. A total of 100 pregnant women up to 12 weeks of gestation wanting termination of pregnancy was recruited in this study. The efficacy, outcome, and induction abortion interval were studied in these cases. Results: In our case study 76% of the patients had complete abortion with single dose of 800ug Misoprostol and 4 % underwent check curettage due to profuse bleeding and retained products in uterus on USG. 16% of the cases needed second dose of 200ug of Misoprostol. The mean induction to abortion interval was 11.38hrs. 96% of the patients had complete abortion with medical method and only 4% underwent surgical curettage due to profuse bleeding after the single dose. The mean haemoglobin prior to induction was 9.76gm% and post expulsion was 9.59gm % respectively. No statistical difference was noted. The incidence of side effects like nausea, vomiting and diarrhoea was minimal and transitory. No major complications noted. Conclusion: Vaginal PGE1 analogue is very safe and effective method of termination of first trimester of pregnancy. Single high dose of vaginal Misoprostol 800ug is found to be cost -effective with minimal side effects, shorter Induction Abortion interval and a day care procedure with good success rate and can be adopted at community and primary health care units to reduce the maternal morbidity and mortality in developing countries like India due to unwanted pregnancies and unsafe abortions.
Authors and Affiliations
Dr. Punam Glory Moses
Keywords
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