THE USE OF SERUM PROTEIN ELECTROPHORESIS IN DIAGNOSIS OF HORSE DISEASES
Journal Title: Folia Pomeranae Universitatis Technologiae Stetinensis Agricultura Alimentaria Piscaria et Zootechnica - Year 2018, Vol 45, Issue 340
Abstract
The aim of the study was to use serum protein electrophoresis for a preliminary evaluation of the physiological condition of horses and detection of potential diseases. The serum electropherogram of healthy horses is characterized by a lack of a prealbumin zone, and 6 different bands can be observed: albumin, α1, α2, β1, β2, and γ-globulin. Numerous pathological states in horses, including liver diseases, innate or acquired immune deficiencies, enteropathies and nephropathies associated with protein loss, local or systemic infections, cancers, and parasites can cause changes in the albumin fraction and globulin concentration. The serum protein level can also change significantly in the case of equine babesiosis. In the horses tested the serum content of albumins and three globulin fractions with their subfractions were determined. The total protein concentration and the ratio of albumins to total globulins (A/G) were determined. Serum protein electrophoresis in horses can be recommended as a screening test for qualitative detection of abnormalities in the major proteins and as an important supplement to detailed calculation of serum proteins.
Authors and Affiliations
Bartosz JANIA, AMELIA WYGANOWSKA, Katarzyna ANDRASZEK
Keywords
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