Thiazolidinediones - Emerging Anticonvulsant with Other Pharmacological Activity Hetrocyclic Scaffold
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2017, Vol 2, Issue 1
Abstract
Thiazolidinediones (TZDs) are five-membered heterocyclic having sulfur, nitrogen, and oxygen atoms in their cyclic ring structure has drawn attention because of its diverse pharmacologically activities connected with it. A lot of research work has been done on various thiazolidinone derivatives for synthetic schemes and biological activities of its novel derivatives. The thiazolidinediones is not only synthetically important scaffold but also possesses a wide range of promising biological activities i.e antimicrobial, anti-inflammatory, anticonvulsant, antimalarial, analgesic, anti-HIV and anticancer action. Some thiazolidinediones derivatives have better activity than standard drug and could become a new drug for the market in future.
Authors and Affiliations
Ruchi Poria
Analysis of Acceptance, Efficacy and Retention Rate of Postpartum Intrauterine Contraceptive Device
Background: Postpartum intrauterine contraceptive device is an effective form of long acting reversible contraception. This study was done to determine the level of acceptance among Indian women according to their socio...
Classification of Connective Tissue Stains.
Connective tissue comprises a diverse group of cells within a tissue-specific extracellular matrix. Connective tissue stains are used for staining connective tissue components. The special stains commonly used for staini...
Study to Assess C Reactive Protein as a Biochemical Severity Marker for Acute Pancreatitis
Majority of Acute pancreatitis are due to gall stone induced(1) and alcohol induced (2). Various theories have been proposed for the mechanism involved in pancreatitis like Bile reflux (3) from CBD to main pancreatic duc...
Role of USG Patients with Acute Abdomen in a district hospital Western Rajasthan
Background: Acute abdomen is the common cause of emergency admissions. USG plays an important role in the diagnosis of disease. Material and Methods: This study was done on patient presented with acute abdomen in Departm...
Fetomaternal Outcome in Placenta Previa
Background: Prevalence of Placenta previa is found to vary between 0.5% of all pregnancies. Placenta previa is one of the major causes of antepartum hemorrhage and is also important cause of maternal and perinatal morbid...